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Until a couple months ago, these medications were only available as injectables, which discouraged some patients

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High blood pressure High blood pressure is thought to increase the thickness and stiffness of the left ventricular walls over time, which changes the way in which electrical impulses travel through the heart (MayoClinic 2011a)

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Either Trx and TrxRD are expressed as isoforms for both predominantly cytosolic (Trx1 and TrxRD1) or mitochondrial (Trx2 and TrxRD2) localization (Enoksson et al., 2005)