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In addition, the results of the ELIXA study answered the question of cardiovascular safety related to heart failure by displaying no significant between-group differences in the rate of hospitalization for heart failure (HR, 0.96
The unsaturation in the linker, which provides conformational flexibility, is particularly important for its antitumor and anticancer effects, though it is less critical for its redox regulatory or apoptotic activities (80)
If a hypersensitivity reaction is suspected, discontinue JANUVIA, assess for other potential causes for the event, and institute alternative treatment for diabetes