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J Urol 97 : 874875 Montorsi F et al

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The global expansion of GLP-1 receptor agonists and related anti-obesity therapies represents a triumph of translational metabolic science

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It lands on Schedule IV due to its phentermine component and has warnings about use in the setting of cardiovascular disease, in addition to concerns about topiramate side effects that include drowsiness, changes in sensation, and kidney stones