To determine whether DAT is a target of AA oxidative products (for example, -KAs) and whether this interaction is relevant for its function, we conducted experiments using synthetic isoketals (IsoK)
Additionally, liver volume decreased significantly, and improvements were observed in biomarkers of hepatic injury and inflammation, suggesting potential antifibrotic and anti-inflammatory properties in these models
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At the same time, the patient was started on meningitis therapy (cefotaxime 3 g every six hours, meropenem 2 g every 8 hours, vancomycine 2 g per day, antimycotics - fluconasol 20 mg every six hours, antiswelling treatment 100 mL of 20% mannitol every six hours) and hydrocortisone supplementation (50 mg every eight hours) to prevent presupposed vascular collapse due to secondary adrenal insufficiency
