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For that, cortical neurons (10 10 5 cells/well) were cultured in Neurobasal medium and treated accordingly with different compounds of interest

Within its role as the bodys most important antioxidant, Glutathione is capable of preventing damage to important cellular components caused by reactive oxygen species (such as free radicals, peroxides, lipid peroxides), xenobiotics, and heavy metals Glutathione also plays important roles in nutrient metabolism, and regulation of cellular events including

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We further determined that Norleual-AngIVs mechanism of action as a Met antagonist is by blocking HGF dimerization which, as indicated above, is a prerequisite to binding and activation of the Met receptor [82,83]

We use the profile-likelihood approach as presented in 48 to determine non-identifiable parameters and compute confidence intervals