In the SCALE Kids trial, daily liraglutide 3.0 mg produced a mean 5.8% BMI change (vs
10.1002/hep.28251 129 SunX.OuZ.XieM.KangR.FanY.NiuX.et al (2015)
However, there is some debate regarding its effectiveness since glutathione may be broken down in the digestive tract before it can be utilized by the body
A 2024 study published in The Lancet Diabetes & Endocrinology reported that patients taking tirzepatide for one year showed significant improvements in cardiovascular risk factors (including blood pressure, cholesterol levels, and insulin sensitivity)
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As this indication is recent, universal prior authorization criteria for drug approval are still uncertain and can vary by state and insurance policy