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Treatment: Symptom-focused, guided by evidence-based consensus (e.g., Canadian Consensus Criteria, D-A-CH 2024), yet few neurologists apply these guidelinesdespite evidence level 2 support
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A total of seven participants had a serious adverse event (four in the intervention arm, three in the placebo arm)
Thus, adipose tissue has been shown to be a central driver of T2DM progression, establishing and maintaining a chronic state of low-level inflammation (120)
Aspartate (Asp) and asparagine (Asn) are more often manifested in the macrophage metabolic network as an associated module of mitochondrial shuttle-nitrogen metabolism-nucleotide synthesis, rather than as a pathway characterized by the output of a single effector molecule
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