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To further address the issue of whether metformin can prevent MG-induced cell apoptosis, we pre-incubated RINm5F cells in different concentrations of metformin (10, 25, 50, and 100 M) in the presence of 1 mM MG

Recent research highlights the intricate relationship between CKD and cardiovascular disease (CVD), acknowledged as a significant risk factor for unfavorable cardiovascular consequences

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NRF2 also actively represses the transcription of pro-inflammatory genes in macrophages

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Additionally, during the MCT-DS phase, significant differences were observed between R and NR