Morning injections allow you to track your appetite response throughout the day, while evening injections may align better with dinner preparation and overnight fasting
Authors contributions Conceptualization and study design (TP, PP, ST), data acquisition (TP, ST), initial drafting of the manuscript (TP, ST), critical assessment of the manuscript and provision of intellectual input (TP, PP, ST)
Your provider will adjust timing based on outcomes and tolerability
As a general guide, you may be suitable if you have: A body mass index (BMI) of 30 or above, or A BMI between 27 and 30 with at least one weight-related condition, such as high blood pressure, high cholesterol or type 2 diabetes
Certain medical conditions, such as gastroesophageal reflux disease (GERD) and sinusitis, may also cause it
Optimized Intermittent Fasting (The 12-Hour Base) While intense 16:8 fasting is popular, 2026 protocols suggest a more flexible approach when combined with medication: The "Gentle Fast": A 12-hour overnight fast (e.g., 7 PM to 7 AM) provides metabolic benefits without the risk of undereating or hypoglycemia
