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Liver repair and regeneration exhibit several commonalities across different conditions, such as the activation of inflammatory and growth factor signaling pathways, including TNF-, IL-6, HGF, and EGF, which play crucial roles in hepatocyte proliferation and tissue repair

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Thus, the effect of CK1, PKC, and p38 MAPK varies from pro-survival in some erythrocyte precursors to pro-eryptotic in mature cells, which might be a consequence of missing downstream effectors in circulating erythrocytes

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