PQQ is involved in the synthesis of sirtuin-related proteins and by maintaining NAD + levels optimizes NAD + which is a cofactor and cosubstrate of sirtuin [380, 381]
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Menzies Institute for Medical Research, University of Tasmania, Hobart, Tasmania 7000, Australia 8
To view a copy of this licence, visit About this article Cite this article Zhuang, Y., Lyu, T., Chen, Y
So, by muting that signal too aggressively, NSAIDs can lead to weaker tissue repair [1, 5]