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NNMT is overexpressed in adipose tissue of obese subjects, and its inhibition has been explored as a strategy to modulate methyl group flux and NAD+ precursor availability

5-Amino-1MQ has been examined in laboratory research studies as an inhibitor of NNMT, an enzyme associated with cellular metabolic pathways

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It is known for its potent anti-inflammatory properties and its ability to promote cell migration to sites of injury