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These include a body mass index (BMI) of 35 kg/m or above (or 32.5 kg/m or above for people from South Asian, Chinese, other Asian, Middle Eastern, Black African, or African-Caribbean backgrounds) with at least one weight-related comorbidity, and previous unsuccessful attempts at weight loss through diet and exercise

Studies are also finding that using a GLP-1 agonist is linked to lowering the risk of heart attack, heart disease, stroke, and kidney disease

J Pathol 244(3):346357 Koch K, Hartmann R, Tsiampali J et al (2020) A comparative pharmaco-metabolomic study of glutaminase inhibitors in glioma stem-like cells confirms biological effectiveness but reveals differences in target-specificity

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Individual risk assessment remains important when initiating any weight management therapy