This multi-target design represents a significant advance beyond both the single-agonist GLP-1 receptor agonists (such as semaglutide) and the dual GIP/GLP-1 agonists (such as tirzepatide)
Tirzepatides dual agonism leads to several interconnected physiological benefits
Answering these helps prioritize hydration, nutrition, sleep, or a medication check with your clinician
doi: 10.1038/nrendo.2017.39
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No adverse effects on male or female fertility were observed in rats at doses up to 100 mg/kg (approximately 4 to 8 times male and female MRHD exposures of phentermine and topiramate extended-release based on AUC)