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Modulation of GLP-1 signaling as a novel therapeutic approach in the treatment of alzheimers disease pathology

Cognitive decline, dementia, and Alzheimer's disease The occurrence of vitamin B 12 deficiency prevails in the elderly population and has been frequently associated with Alzheimer's disease (reviewed in 63, 64)

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Overall, the modular design of COFs enables precise integration of multiple functional components, including photosensitizers (e.g., porphyrins), enzyme-mimicking catalytic sites, and stimuli-responsive linkages, into a single framework

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This phenomenon was highlighted in the SUSTAIN-6 trial, where patients with advanced baseline DR who experienced rapid HbA1c declines on semaglutide had higher rates of retinopathy progression compared to controls