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Additionally, mitochondrial DNA copy number alterations and mutations have been observed in therapy-resistant CSC populations, further reinforcing their reliance on oxidative metabolism

The neuroprogressive nature of major depressive disorder: pathways to disease evolution and resistance, and therapeutic implications

Genetic redundancy within the pathway Given the genetic complexity of the pathway (Table 1), gene-specific Arabidopsis mutants have been very useful in defining the importance of the different isoforms

Hydroxyproline (HYP) assay Fresh lungs of young or aged fibrotic mice were fully perfused with PBS

If the tumor specimen consists mainly of neuroblastoma-like cells, with suspected malignancy upon clinical evaluation, it should be classified as a small round cell tumor arising in infancy, such as neuroblastoma or rhabdomyosarcoma (12)

At what point does this become absolutely unsustainable