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Compared with placebo, semaglutide reduced the risk of the first occurrence of MACE and each MACE component consistently across all subgroups (gender, age, and baseline CV risk profile)

Week 3 (escalate): 7.5 mg = 0.75 mL (75 units)

Further research has found that these rates may be even higher in the real world, especially for people with obesity taking semaglutide or other GLP-1s for weight loss

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Pioglitazone is a PPAR gamma agonist (thiazolidinedione) that has been shown to reduce the occurrence of hepatic steatosis and lobular inflammation 45 and has cardiometabolic benefits

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