Because phosphatidylcholine is required in the synthesis of very-low-density lipoprotein (VLDL) particles (see Function), choline deficiency results in impaired VLDL secretion and accumulation of fat in the liver (steatosis), ultimately leading to liver damage
Watson, Z
This reduction was specific to visceral fat , not subcutaneous fat
T2D is, however, a multifactorial disease with alterations in lipid and protein metabolism as well as complex interactions between organs, tissues, cell types, and subcellular compartments/organelles
Analyses of relevant research In recent years, numerous studies have investigated the therapeutic targets and mechanisms of Chinese medicine in treating depression by integrating proteomics with experimental validation
CrossRef van Bruggen FH, McIntyre RS