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[7] However, the use of GLP-1 agonists during pregnancy and lactation is less well understood, as these groups are typically excluded from clinical trials

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For now, it is available only for research purposes

It may be useful in patients who have achieved their goal weight and are using lower doses to maintain their weight. However, early data and clinical experience suggest that it is an effective strategy, Orandi commented

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Comparator Selection : Many trials use placebo comparisons rather than active comparators, limiting understanding of relative effectiveness compared to existing obesity treatments