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In a reactor having an inert atmosphere, e.g., nitrogen, a slurry of 9-(2-hydroxyethyl)adenine (1.0 kg) and DMF (4.79 kg) is warmed to about 130 (125-135) for 30-60 minutes

The N-terminal sequence of exendin-P5 differs considerably to the other peptides and is also extended by one residue (Figure 1A)

Over time, this can complicate weight maintenance, even when food choices themselves havent changed

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