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Definitions Gout Gout is defined as a disorder resulting from tissue deposition of MSU crystals (in joints, bursae, bone and certain other soft tissues, such as ligaments, tendons, and, occasionally, skin) and/or crystallization of uric acid within the renal collecting system (tubules and renal pelvis) that typically occurs in acid urine ( Table 1 - 1 )
Collectively, these mechanisms support the therapeutic potential of GLP-1RAs in preventing and treating SIM (58)
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In their experimental study of rats exposed to the substances for 90 days, changes in the temporal cortex and hippocampus were analysed
Thus, human spermatozoa possess a capacity to reduce the probe WST-1 in the presence of an intermediate electron acceptor in a similar fashion to the plasma membrane redox system described in somatic cells by Berridge and Tan [54, 55]
