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After reaching their goal weight on 12mg, they gradually reduce to 8mg or even 4mg as a maintenance dose

Some patients start with semaglutide and switch to tirzepatide if they plateau

These numbers are unusually strong for a nonrandomized oncology-adjacent study, which is exactly why they are both intriguing and difficult to accept at face value

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There is currently no cure for gastroparesis, and treatments generally provide only limited symptom relief

In addition, researchers found that participants cardiometabolic improvements reverted once their weight returned to their baseline and they regained what they had just lost