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Fat Oxidation and Weight Loss (Animal Data) Evidence quality: Moderate (multiple animal studies) In obese mice, chronic treatment with AOD-9604 significantly reduced body weight gain and increased fat oxidation (Heffernan et al., 2001)
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These results suggest that GHR expression in AgRP neurons is unnecessary for the regulation of energy homeostasis under normal circumstances or for the response to key hormones that rely on AgRP neurons to modulate energy homeostasis
Rapid correction of deficiency is required
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