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Moreover, the specificity of curcumins epigenetic actions remains uncertain

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TNF- (0250 pg/mL) was exposed for 6 h to differentiated myotubes

A 2.5 mg dose is 2.5 10 = 0.25 mL = 25 units

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This approach has been used to show that proteasome concentrations in peripheral blood are elevated in patients with certain types of malignant diseases, including multiple myeloma, suggesting that circulating proteasome levels may be correlated with tumour burden