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"But studies have found that a BMI higher than 25 increases ones risk for heart disease, type two diabetes, and some forms of cancer

or chronic viral, bacterial, yeast, or parasite infections

Regarding the neuroinflammation, VD induces the transcription of thioredoxin superfamily member 4 (THEM4) and subsequently inhibits Akt phosphorylation and the NF-B pathway, ultimately resulting in the down-regulation of IL-1, IL-2, IL-6, IL-8, TNF- and COX expression

doi: 10.1016/S0022-2828(85)80130-9

Load up on the veggies for volume and nutrients without excessive fat that can trigger nausea

Each category works through a different mechanism, carries a different level of clinical evidence, and comes with its own cost and safety considerations, so understanding the distinction matters before choosing one