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Absorption rates improve with supplementation

Glucose intolerance and insulin resistance occurred in mice exposed to oral carrageenan and were attributable to disruption of intracellular insulin signaling and activation of inflammatory pathways [10]

This isnt surprising considering the beneficial effects it has on nitric oxide levels and blood flow

10.1186/s40779-022-00383-2 Summary Keywords ischemic stroke, Lithocarpus polystachyus Rehd., pyroptosis, PI3K/Akt/NF-B, oxidative stress, inflammation Citation Liu D, Wu W, Wang T, Zhan G, Zhang Y, Gao J and Gong Q (2024) Lithocarpus polystachyus Rehd

When this happens, it creates a backup that can damage the kidneys, create bladder stones or lead to bladder infections

Think muscle, not just weight