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4-Pantetheinylation of formyltetrahydrofolate dehydrogenase (FDH) The figure shows two reactions involving FDH: Panel A: Holo-FDH (the biologically active FDH) catalyzes the conversion of 10-formyltetrahydrofolate into tetrahydrofolate using water and NADP + , releasing CO 2 , NADPH, and a proton (H + )

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To our knowledge, this is the first study to examine the effect of GLP-1 RA use on RA disease activity and cardiovascular risk profile in patients with RA and overweight or obesity, the researchers wrote