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This may be linked to changes in food intake or the body adjusting to lower blood sugar levels

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However, as mentioned above, many types of receptors with different biological effects have already been discovered, and little is known about which receptors are appropriate targets for NAFLD therapy

In April 2026 the sponsor announced positive topline results from the Phase 3 SYNCHRONIZE-1 obesity trial, but those company-reported data await full peer-reviewed publication and are best treated as preliminary until then

The National Institutes of Health operates a searchable database at ClinicalTrials.gov for active studies involving GLP-1 medications