2: Mitochondrial GSH import is mediated by SLC25A39
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Comment forever for the research
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Tirzepatide was developed as a unimolecular dual agonist and moved through the SURPASS (type 2 diabetes) and SURMOUNT (obesity) Phase 3 programs to approval, becoming the first approved GLP-1/GIP dual agonist
Therefore, we failed to obtain the optimal cut-offs of serum GPX-3 concentration for all-cause mortality, ESKD, CVA, or ACS in this study (Supplementary Figure S1)