In man, UA is the final product of purine catabolism ( DUAL ROLES OF URIC ACID IN AODS Contrary to the traditional understanding as a metabolically inert and waste compound without any physiological significance, UA is a natural antioxidant contributing to approximately 60% of the free radical scavenging activity in human blood ( Uric acid is a selective antioxidant ( Figure 3 ) that removes superoxide by preventing the degradation of superoxide dismutase and subsequently inhibits its reaction with NO to form peroxynitrite ( + -induced depolarization amplifies neuroprotection provided by UA through a mechanism involving Ca 2 elevation and extracellular signal-regulated kinases (ERK 1/2 ) activation ( Figure 3 )
Therefore, increasing the dose too quickly can cause severe side effects such as headache, nausea, vomiting, and diarrhea
Learn how Omega 3 rich foods like fish oil, salmon, walnuts, & more can boost brain power, save
A PubMed Central-hosted review of peptide-based obesity treatments describes "nausea, vomiting and loss of appetite" as common effects of the GLP-1 drug class (pmc.ncbi.nlm.nih.gov)
Eur J Endocrinol
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