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Discontinuation rates of 1218% at the highest doses were partially attributed to patients losing more weight than was clinically appropriate for their starting BMI

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This combination may interact with chemotherapy medicines (like doxorubicin and cisplatin), aluminum-containing antacids (like maalox), estrogen-containing medications (like estradiol), protease inhibitors (like indinavir), statins (like atorvastatin) and anticoagulants (like warfarin)

Instead of viewing sweets as forbidden, most patients find success by noticing genuine fullness cues that the medication amplifies, then stopping when satisfied rather than finishing portions out of habit