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From 4-week old, mice were fed with a high-fat diet (D12492, Research Diets, USA) for 5 months, switched to above MCR or CTR diets for 4 months, and then switched back to HFD for additional 2 months

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Although relatively rare, the clinical morphology of pediatric melanoma is similar to that of adults

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Long interested in Holst's work, in 1990 Novo Nordisk recruited his colleague Schwartz to develop small molecules able to activate the GLP receptor in the pancreas (Molteni, Chen)