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Patients who should wait before starting BPC-157: those with active malignancy or a personal history of hormone-sensitive cancer, pregnant patients, and anyone who has not yet completed a basic anti-inflammatory protocol for an acute injury

B12 itself is generally safe, but the side effects often come from the semaglutide

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The procedure note must identify the specific bone being sampled and describe why the biopsy was medically necessary, such as concern for infection, malignancy, or unexplained bone lesions

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However, due to rare but serious adverse effects (e.g., thrombocytopenia, cardiac arrhythmias, hypersensitivity reactions), many guidelines recommend against routine use