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To decrease this risk, regularly use a sunscreen with a Broad Spectrum SPF value of 15 or higher and other sun protection measures including

A genetic disorder where red blood cells (RBCs) lack enough G6PD enzyme, making them vulnerable to oxidative stress, leading to hemolytic anemia

A chronic TFCC tear may result from normal wear associated with aging or an inflammatory condition such as gout or rheumatoid arthritis

Constipation affects about 18% of users

These metabolic effects are reinforced by anti-inflammatory and antifibrotic actions, partly through the FGF21 adiponectin axis