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Dena M, Svensson AM, Olofsson KE et al (2021) Renal complications and duration of diabetes: an international comparison in persons with type 1 diabetes

TRT is also not recommended if you have heart issues including: Uncontrolled heart failure A recent heart attack (within six months) Untreated high blood pressure Patients with other cardiac issues, if well managed, may be treated but require close cardiac monitoring, says Staheli TRT may also not be advised if you have sleep apnea

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Transdermal drug delivery: innovative pharmaceutical developments based on disruption of the barrier properties of the stratum corneum