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4.3 The potential of peptide-based redevelopment of dendritic cell vaccines After considerable endeavors, sipuleucel-T stands alone as the immunotherapeutic agent that has yielded a significant survival benefit in a randomized Phase 3 clinical trial (Kantoff et al., 2010)

2001 Feb;60(2):109-20

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46 However, the effects may vary at different stages of the disease, as evidenced by the study showing that the reduction was most pronounced in the early stages but less so in more advanced stages with behavioral symptoms

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