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In some embodiments, the ear is the outer ear, middle ear, or inner ear

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This translates to functional differences

[DOI] [PMC free article] [PubMed] [Google Scholar] 111.Li L., Prabhakaran K., Zhang X., Zhang L., Liu H., Borowitz J.L., Isom G.E

Biomolecules 11 , 1667 (2021)

Two structural modifications distinguish this analog from the parent tridecapeptide: substitution of Met-4 with norleucine (Nle) and inversion of Phe-7 to the D-enantiomer, both of which are widely documented in the peptide chemistry literature as means of increasing conformational and oxidative stability of the reference standard