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Abstract Objective: Having demonstrated short-term weight loss with liraglutide in this group of obese adults, we now evaluate safety/tolerability (primary outcome) and long-term efficacy for sustaining weight loss (secondary outcome) over 2 years

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It is worth noting that fatigue was not a primary endpoint in pivotal studies, so specific clinical trial data quantifying its duration is limited

The timeline for appetite suppression with Semaglutide GLP-1 can vary from person to person