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Rapid fat mobilization during active weight loss increases circulating inflammatory markers and fatty acids, which can trigger temporary skin sensitivity

The improvements observed were largely attributed to weight loss and metabolic correction rather than direct drug effects on ovarian tissue

Whichever the measure, the real goal is to get out of the obese range, not necessarily to get out of the overweight range

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The genetic basis of metabolic disease

Our study showed that palmitoyl-L-carnitine influences mitochondrial fission by promoting the phosphorylation of DRP1 and MFF, increasing MFF expression, without altering DRP1 protein levels (Fig 3)