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Timing considerations Morning and evening applications are common for twice-daily protocols

If skin does look or feel worse after starting 1% GHK-Cu Face and Skin Serum, reducing frequency further (back to every other day, or every third day, for example) rather than stopping entirely is a reasonable next step if the change is mild, since it allows the skin to continue adjusting at a slower pace

It is hypothesized that catechins, especially EGCG, directly inhibit catechol-O-methyltransferase, an enzyme that breaks down norepinephrine, in order to enhance fat oxidation (Borchardt and Huber, 1975)

2023;10(28):e2300822

doi: 10.1016/j.animal.2024.101127 107 ReikW.DeanW.WalterJ

doi: 10.1007/s10812-007-0033-8