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Pathohistological analysis After sacrificing the respective tissue was dissected, fixed in buffered formalin (pH 7.4) for 24 hours and embedded in paraffin using standard procedures

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Moreover, peroxidative ROS levels depend on the caution of the antioxidant systems, which shield cells from oxidative harm, incorporate various peroxisomal enzymes, such as catalase (CAT), superoxide dismutase (SOD), glutathione peroxidase (GPX), and peroxiredoxins (PRDX), as well as low molecular weight non-enzymatic antioxidants [17]

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Together our findings suggest that acetylation is a potent mechanism to regulate TrxR1 activity that also allows the enzyme to evade oxidative inactivation