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Neither aspartame nor sucralose cause measurable changes in the gut microbiota or short-chain fatty acid production after 14 days of daily intake of sugar-free energy drinks

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At the highest dose, tesofensine caused a weight reduction of 9.9%

Efficacy & safety of co-administered cagrilintide & semaglutide versus semaglutide alone in adults with #overweight or #obesity with or without type 2 #diabetes in Japan & Taiwan (REDEFINE 5): a multicentre, randomised, active-controlled, phase 3a trial thelancet.com/journals/landi

Notably, the efficacy of atorvastatin is poorly correlated with C max [44], probably due to complex pharmacokinetics of drug metabolites with longer half-life compared to the parent compound