Glutamine synthetase (GS) can maintain the phenotype of M2 macrophages, and the inhibition of GS skews M2-polarized macrophages toward the M1-like phenotype [27]
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88, 89, 90 Furthermore, psychostimulants themselves enhance AA levels and may exacerbate oxidative stress in the brain, 55, 56, 57, 85 possibly increasing the levels of harmful AA metabolites
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After washing with PBS for 2 times, the cells were observed using a confocal microscope
7 Glutathione-mediated regulation of NF-B, MAPK, and PI3K/AKT pathways in cancer progression and metastasis The NF-B, MAPK, and PI3K/AKT pathways are key regulators of tumor growth, resistance to oxidative stress, and metastasis, operating through redox-sensitive signaling mechanisms
