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"Stability of buffer-free freeze-dried formulations: a feasibility study of selected pharmaceutically relevant proteins." European Journal of Pharmaceutics and Biopharmaceutics

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J Clin Endocrinol Metab 96:20272031 Contribution statement SM and RRH both contributed to the conception and design of this article

A comparison of semaglutide and tirzepatide Feature Semaglutide Tirzepatide FDA Approval Year 2017 (injection), 2020 (oral) 2022 Average Weight Loss ~1015% of body weight ~1520% of body weight Dosage Forms Weekly injection, oral tablet Weekly injection only Common Side Effects Nausea, vomiting, diarrhea, constipation Nausea, vomiting, diarrhea, constipation Frequency Weekly (injection), daily (oral) Weekly injection Cost (approximate) $900$1,200/month $1,000$1,300/month (Keep in mind that numbers are averages