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The signal transducer and activator of transcription 3 (STAT3) protein is a transcription factor known to stimulate immunosuppressive cells, e.g., myeloid-derived suppressor cells (MDSC) and regulatory T cells (Treg), activated in chronic inflammatory conditions [8, 9]

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Alogliptin inhibits IL-1beta-induced inflammatory response in fibroblast-like synoviocytes

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Regenerative priming: Brief BPC-157 exposure may reprogramme cellular responses (e.g., activating quiescent fibroblast populations) in a way that persists after peptide clearance