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Gut commensal Parabacteroides goldsteinii plays a predominant role in the anti-obesity effects of polysaccharides isolated from Hirsutella sinensis

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Activation of these enzymes under pathological conditions increases the levels of ROS, which in turn activate several cellular signaling factors such as nuclear factorB (NF-B), MAPK, Akt/PKB and tyrosine kinases

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Conversely, when L-arginine, a precursor to NO that increases its production, was given, BPC-157 also appeared to exert a normalizing effect