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Based on existing evidence, it is anticipated that participants undergoing immediate treatment cessation will experience significant weight regain, consistent with previous trials demonstrating that a substantial proportion of lost weight is regained following withdrawal of pharmacological therapy [11,12]

How GLP-1 therapies work, the mechanism GLP-1 receptor agonists work through several complementary mechanisms

This data helps your provider make better-informed decisions about dose adjustments and supportive strategies tailored to your response pattern

14 Diabetes is an endocrine disease characterized by abnormally high blood glucose levels

These drugs work by mimicking the effect of a hormone called glucagon-like peptide-1 (GLP-1), which helps control blood sugar levels and promotes weight loss

Materials and methods: DM was induced in male C57BL/6 ApoE -/- mice (n=20) via intraperitoneal streptozotocin (STZ) injection (0.05 mg/g bodyweight) for 5 consecutive days