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Core Methodology: Structural Template: The experimental structure of the GLP-1-GLP-1R interaction (PDB entry 4ZGM) serves as the structural basis for designing semaglutide analogues

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These observations have prompted interest in its relevance to experimental models of intestinal barrier impairment

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Gastrointestinal problems such as nausea were the most common side effects, which totaled 25.5% of all adverse events in the liraglutide group