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Hepatology 31 , 391398, doi: 10.1002/hep.510310219 (2000)

IL-10, an anti-inflammatory cytokine, increases

No pathological changes, such as inflammation or ulceration, were observed

The age-related decline in melatonin and dampening of circadian rhythms likely contributes to sleep problems, metabolic and cognitive decline, and increased vulnerability to age-related diseases