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A recent meta-analysis of 12 observational studies found that higher dietary intake of vitamin B 12 was associated with a 23% lower risk of depression compared to lower intakes, but stratifying the data revealed a significant protective association in females, not in males (99)

However, human studies have not yet examined this mechanism in detail

It participates in over 500 enzymatic reactions and is essential for energy production, DNA repair, and cellular signaling

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Bloating affects 2-5% of users but typically normalizes within the first week